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Takotsubo-like cardiomyopathy: clinical features, diagnosis, prognosis and follow-up


An observational study has attempted to identify appropriate elements that may contribute to clarify the broad clinical features ( diagnosis, care, complication and prognosis ) of Takotsubo-like cardiomyopathy for improving its management.

During the period 2004-2010, 84 consecutive patients were diagnosed for suspected Takotsubo-like cardiomyopathy at the Vannini Hospital in Rome ( Italy ).
To be eligible, patients had to meet all the Mayo clinic criteria in the absence of neurological trauma or intracranial haemorrhage. Moreover, those patients that at follow-up still presented alteration of acute phase at ECG and echocardiogram were excluded. Thus, 75 patients comprised the study population. To follow-up 19 patients were lost.

The study population consisted of 75 patients, 72 of the them were women and 3 were men with a mean age of 71.9±9.6 years.

: None of 75 patients died in acute phase. All patients were promptly discharged ( 8.4±4.4 days ), since they recovered their normal functional status without symptoms.

Follow-up information was available for 56 patients.

At a mean follow-up time of 2.2±2 years ( range, 0.1-6.8 years ) two octogenarian patients ( 2.6% ) died because of sudden cardiac death and pulmonary embolism, respectively.
The Takotsubo-like cardiomyopathy recurred in one patient.

The results of this study support the previous reports about the good prognosis, also in critically ill patients, of Takotsubo-like cardiomyopathy. ( Xagena )

Cacciotti L et al, BMJ Open. 2012 Oct 11;2(5). pii: e001165. doi: 10.1136/bmjopen-2012-001165.

XagenaMedicine_2012



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