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Heart disease patients with symptomatic COVID-19 are often treated with Nirmatrelvir - Ritonavir ( Paxlovid ) to prevent progression to severe disease; however, it can interact with some previously pr ...


Mixed effects of fish oil supplementation on the risks of atrial fibrillation were observed in several large-scale randomized controlled trials. Whether this relationship would be modified by geneti ...


Results from animal models and observational studies have raised concerns regarding the potential cataractogenic effects of statin treatment. A study has investigated whether common and rare genetic ...


Gout is a common comorbidity in heart failure ( HF ) patients and is frequently associated with acute exacerbations during treatment for decompensated HF. Although Colchicine is often used to manage ...


Class 1C antiarrhythmic drugs ( AAD ) have been associated with harm in patients treated for ventricular arrhythmias with a prior myocardial infarction. Consensus guidelines have advocated that thes ...


The relationship between statin ( HMG-CoA reductase inhibitors ) treatment and Coronavirus Disease 2019 ( COVID-19 ) mortality has been discussed due to the pleiotropic effects of statins on coagulati ...


The Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMA ) has granted a positive opinion for Vericiguat ( Verquvo ), a soluble guanylate cyclase ( sGC ) stim ...


Major bleeding after acute coronary syndrome predicts a poor outcome but is challenging to define. The choice of antiplatelet influences bleeding risk. Major bleeding, subsequent myocardial infarct ...


Interim results from the ongoing phase 1 study of ALN-AGT, a subcutaneous investigational RNAi therapeutic targeting liver-expressed angiotensinogen ( AGT ) for the treatment of hypertension, were ann ...


Troponin elevation is common in hospitalized COVID-19 patients, but underlying aetiologies are ill-defined. Researchers have used multi-parametric cardiovascular magnetic resonance ( CMR ) to assess ...


The effects of direct oral anticoagulants in nonvalvular atrial fibrillation should be assessed in actual conditions of use. France has near-universal healthcare coverage with a unified healthcare i ...


Mavacamten improves heart function and symptoms in patients with obstructive hypertrophic cardiomyopathy ( HCM ), according to results from the EXPLORER-HCM trial. Currently available medical treat ...


The coronavirus disease 2019 ( COVID-19 ) pandemic has resulted in severe psychological, social, and economic stress in people’s lives. It is not known whether the stress of the pandemic is associated ...



New data from a sub-analysis of the landmark phase III DAPA-HF ( Dapagliflozin And Prevention of Adverse-outcomes in Heart Failure ) trial have shown that Dapagliflozin ( Farxiga ) has reduced the inc ...