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The CANVAS trial has shown that Canagliflozin ( Invokana ) was superior to placebo at preventing cardiovascular events. The goal of the trial was to evaluate the sodium-glucose cotransporter 2 inhi ...


Although procedure-related deaths during index admission following catheter ablation of atrial fibrillation ( AF ) have been reported to be low, adverse outcomes can occur after discharge. There are ...


The aim of study was to compare effectiveness and safety of non-vitamin K antagonist oral anticoagulants ( NOACs ) versus vitamin-K antagonists ( VKA ) in atrial fibrillation ( AF) patients with chron ...


Ivabradine ( Corlanor ) has been approved in heart failure with reduced ejection fraction ( HFrEF ) and elevated heart rate despite guideline-directed medical therapy ( GDMT ) to reduce cardiovascular ...


The GLOBAL LEADERS ( GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation ) trial randomly assigned 15,991 patients undergoing percutaneous coronary i ...


The number of patients with heart failure with preserved ejection fraction is on the rise, and the search is on for a therapy that can improve health outcomes in this group of patients for whom no app ...


A study has shown that opening all clogged arteries with stents after a serious myocardial infarction is much better than opening only the single clogged artery that caused the infarction. About ha ...


Atrial fibrillation is the most frequent sustained arrhythmia. Atrial fibrillation often recurs after restoration of normal sinus rhythm. Antiarrhythmic drugs have been widely used to prevent recurr ...


Prasugrel ( Efient ) is superior to Ticagrelor ( Brilique ) for reducing ischaemic events in patients with acute coronary syndrome and a planned invasive strategy. The results of the ISAR-REACT 5 tr ...


The combination of Ticagrelor ( Brilique ) and Aspirin ( Acetylsalicylic acid ) reduces ischaemic events compared with Aspirin alone in patients with stable coronary artery disease and diabetes. The ...


Implantable cardioverter-defibrillator ( ICD ) use is associated with reduced short- and long-term mortality in patients with heart failure. Patients with heart failure are at increased risk of pot ...


Subcutaneous administration of Inclisiran, a small-interfering RNA ( siRNA ) directed against proprotein convertase subtilisin/kexin type 9 ( PCSK9 ), was associated with substantial and sustained low ...


Edoxaban ( Lixiana ) in combination with a P2Y12 inhibitor is noninferior to standard triple therapy for preventing bleeding in patients with atrial fibrillation after coronary stenting. The results ...


At the European Society of Cardiology Congress 2019, researchers from Brigham and Women's Hospital and Greater Paris University Hospitals - AP-HP/Université de Paris, have presented the results from T ...


A large Cleveland Clinic study has shown that weight-loss surgery performed in patients with type 2 diabetes and obesity is associated with a lower risk of death and major adverse cardiovascular event ...